A stunning 85th-minute equaliser from Eduard Bello earned Venezuela a rare draw at Brazil.
Brazil took the lead when Neymar had a shot pushed wide in the 49th minute, and from the resulting corner, taken by the striker, Arsenal defender Gabriel rose at the near post to angle home a fine header.
The goal forced Venezuela into a more adventurous approach, and Wilker Angel flashed a header just wide from a 62nd-minute corner.
AS IT HAPPENED: Brazil 1-1 Venezuela Highlights
Rodrygo then found himself in a great position in the box, but the Real Madrid winger blasted his shot into the side-netting.
With five minutes left, the home crowd in Cuiaba were left stunned when Jefferson Savarino whipped in a cross, and Bello leapt acrobatically to blast a spectacular overhead kick past Ederson.
The result leaves Brazil in second place in the 10-team qualifying standings, two ahead of Colombia and two behind Argentina.